Glycine Powder 1Kg | Pure L-Glycine | Vegan Friendly, GMO Free

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The body’s built-in antioxidant system is dynamic, being cranked up under certain circumstances (such as during an infection) and down regulated under others. A key regulatory pathway is controlled by Nrf2 signalling. In many glycine supplementation studies, Nrf2 has been shown to be up-regulated by glycine supplementation. [ Wang, 2019]

A detailed study of the body’s glycine requirements compared to the amount available from glycine synthesis and diet suggests that the adult body runs a deficit of about 10g per day. [ Meléndez-Hevia et al, 2009] Have you ever wondered why you don’t physically act out your dreams while you sleep? You have glycine to thank for that! 30 years ago it was discovered that glycine mediates the suppression of muscle movement during REM sleep. [ Soja, 2008]Glycine ingestion before bedtime has been shown to improve both subjective and objective sleep quality in people who have difficulty sleeping. Furthermore, partially-sleep-deprived subjects who were given glycine before bed had improved daytime performance over those who did not receive glycine. [ Bannai, 2012] Therefore, people with type 2 diabetes may benefit from supplementing with glycine, though research is too preliminary to make any specific recommendations.

Improves insulin response, measured during an euglycemic-hyperinsulinemic clamp; No significant alteration in insulin action

Glycine solution is widely used for irrigation during endoscopic (keyhole) surgery. A complication of such procedures occurs when large volumes of the 1.5% glycine solution become inadvertently absorbed into circulation. This can lead to toxic levels of glycine in the blood which may cause serious complications including transient blindness or even death, although such effects are partly due to dilution of electrolytes, not just the glycine concentration. [ Olsson & Hahn, 1998] Such results can be repeated in animals via intravenous infusion of 1.5% glycine solution. Alves at al, Nutrients, 2019 Glycine Metabolism and Its Alterations in Obesity and Metabolic Diseases]