Healthspan Vein Vine 360mg (90 Tablets) | for Tired & Heavy Legs | Maintains Healthy Leg-Vein Functions | Red Vine Leaf Extract | Added Vitamins B1 & C | Vegan

Product Information

In terms of safety and tolerance, red vine leaf extract proved good or satisfactory, which was expected from a flavonoid-rich natural product. Natural remedies for heavy, tired legs, water retention and cellulite This means that the person no longer suffers from the pain that comes with the conditions. It also minimized the pain and tingling sensations in the legs. The leaves of the grape vine (Vitis vinifera) are an increasingly popular culinary vegetable, used in a variety of recipes from cuisines around the world. But more important, vine leaves are an excellent source of powerful antioxidant compounds with impressive health effects. The red vine leaf, in particular, has been found to help improve conditions related to poor blood circulation, notably varicose veins and associated symptoms.

Holland & Barrett Leg Vein Formula is carefully developed to help maintain healthy circulation in the legs. The capsules contain Red Vine leaf extract which contributes to good blood flow in the legs, along with grapeseed extract and Vitamin C. The LipoTherapeia® treatment is exclusively provided at our practice in Marylebone, London (The Light Centre, Clearwater Court, 49 Marylebone High Street, London, W1U 5HJ) Although the red vine leaf extract studies were small in number, the available evidence suggests that AS 195 has properties that may help to maintain healthy leg-vein function. As such, its role in the prevention of CVI and in ameliorating established venous disease could be further explored. Such investigations may include evaluation of the correction of early vein changes to prevent venous ulceration and the role of red vine leaf extract in maintaining leg-vein integrity, thus leading to enhanced treatment options and a recurrence-prevention strategy. No AI tool has the depth of experience accumulated over tens of thousands of sessions with real human beings (in fact, AI tools have zero experience, obviously). Neither can an AI tool discriminate what is reality and what is made up BS on the web. Formica, J.V., Regelson, W. (1995) Review of the biology of quercetin and related bioflavonoids. Food and Chemical Toxicology; 33: 12, 1061-1080.

About Red Vine Leaf Extract

So if you suffer from CVI, water retention and cellulite, it would be a good idea to consult with a qualified healthcare practitioner regarding the use of red vine leaf extract (as well as centella asiatica/gotu kola extract, hesperidin, diosmin, butcher’s broom extract and escin/horse chestnut extract, among others). One of the first studies to assess the effectiveness of red vine leaf extracts (Antistax) asked 71 people with leg swelling (due to chronic venous insufficiency) to take 360mg red vine leaf extracts, or placebo during two separate periods of 6 weeks. This meant that each person tried both treatments and acted as their own controls.

Safety: Our treatments have proven 99%+ safe over the last 12+ years (with minor/temporary irritation occurring in the other 1%- of treatments). However,as with any medical/aesthetic treatment or skin product,sensitivity varies from person to person, and from time to time even on the same person, depending on lifestyle, genetics and state of health(how each individual body responds to a treatment at a specific time), so we cannot guarantee 100% safety. Drug therapy is a treatment option in incipient and mild to moderate CVI. Leach’s (2004) review of leg ulceration included the evidence for systemic therapy, namely orally administered phlebotonic (venotonic) agents. Such drugs are often plant-derived substances for which an anti-exudative (anti-inflammatory) and anti-oedematous action and efficacy have been confirmed in experimental studies and clinical trials. Experimentally, most have a membrane-stabilising action, leading to a decrease in capillary permeability. Some also have antioxidant properties.Holland & Barrett Leg Vein Formula contains ingredients that help to maintain a healthy circulation and blood flow in the legs. The study lasted for 12 weeks and at the end of that duration, those who were using the red vine leaf extract recorded remarkable improvements in their conditions. The accelerated rate of blood flow from the legs resulted in a drastic reduction in the volumes and circumference of the legs. Food Supplements are intended to supplement the diet and should not be substituted for a varied diet or healthy lifestyle. Not suitable for children under 12. Before taking this product please consult your doctor of pharmacist if you are taking any medication or are pregnant, breastfeeding or trying to become pregnant. In some cases, taking pure vine leaf extracts has been shown to cause gastrointestinal discomforts. However, in most cases these discomforts are relieved naturally within a short time.

Recent studies have investigated the action of flavonoids in preventing atherosclerotic plaques (Hollman and Katan, 1997). Bioflavonoids or flavonoids are a class of water-soluble substances found in a number of plants or plant-derived products. It is believed that flavonoids have a wide range of beneficial effects when taken in the diet, including anti-inflammatory, antihistaminic and antiviral action. Formica and Regelson (1995) concluded that flavonoids are important in the maintenance of capillary wall integrity and resistance. However, this doesn’t mean vine leaves aren’t healthy. There is ample research on the properties and health benefits of red vine leaves and several uses have been identified: Red vine leaf extract, as well as the other natural extracts mentioned above (such as gotu kola extract, horse chestnut extract etc), are quite unknown in the vast majority of the population in the UK and US. Oduncu, H. et al (2004) Effects of compression on blood flow in lower limb wounds. International Wound Journal; 1: 2, 107-113.An earlier (2002) study under the leadership of Dr Stephan Nees found that treating cells damaged by CVI with AS 195 led to the restoration of cell functionality, showing that red vine leaf extract is, at least to a certain extent, able to reverse existing damage in the veins. A source of flavonoids that has undergone extensive preclinical and clinical investigation is the red vine leaf extract AS 195. This has shown that its flavonoids may have significant benefits for patients with pre-ulcer venous hypertension. Red vine leaf extract AS 195 Kiesewetter, H. et al (2000) Efficacy of orally administered extract of red vine leaf AS 195 (folia vitis viniferae) in chronic venous insufficiency (stages I-II). Arzneimittelforschung; 50: 2, 109-117. This product has been improved. At Healthspan we are constantly striving to provide products of the highest quality and sometimes that means we need to make changes to your supplements. Our new and improved Vein-Vine formulation now contains vitamins B1 and C, to support your heart health and blood vessels, while remaining at the same price as before. What is Vein−Vine? The usual dose is 360 mg to 720 mg daily, but follow manufacturer’s instructions as the concentration of red vine leaf extracts vary. Only select supplements made to a pharmaceutical standard known as GMP, as low quality red vine leaf products (on sale in health food shops in Japan) were found to contain low levels of active polyphenols, and inconsistent levels per tablet.

Both the red vine leaves, as well as the skin and the seeds of the grape, contain antioxidant polyphenols. These phytonutrients are capable of counteracting the accumulation of hyper-reactive oxidant species, also known as oxidative stress and responsible for many cellular damages. It is recognized that oxidative stress promotes premature aging of the body. Thus, thanks to their antioxidant power, the polyphenols of the red vine can have many protective effects. There is little research on the nutritional properties of vine leaves. Some studies say they contain good amounts of vitamin C, others that they are a moderate source of calcium or magnesium. Some say they contain healthy Omega-3 fatty acids. However, more research is needed to confirm these facts. Our red vine leaves are harvested when its nutrient content is at its highest; the leaves are then dried and its nutrients extracted using precise temperature controls and purified water, guaranteeing a grapevine extract of the highest quality. Each tablet contains 360mg of natural red vine leaf extract - equivalent to 5,400mg of fresh red vine leaf - including 40% polyphenols, the key ingredient. Take daily for at least six weeks to start seeing the full benefits. Symptoms of chronic venous insufficiency include feelings of heaviness, aching legs, swelling of the ankles or calves, sensations of tension in the legs and pain. The overlying skin may become dry and discoloured and acquires a characteristic mottled pigmentation. Schaefer, E. et al (2003) Oedema-protective properties of the red vine leaf extract AS 195 (folia vitis viniferae) in the treatment of chronic venous insufficiency: a 6-week observational clinical trial. Arzneimittelforschung; 53: 4, 243-246.

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A cooling leg gel containing red vine leaf extracts that is designed to soothe and refresh tired, heavy legs, is also available. In contrast, in France, Germany and Italy these natural extracts have been widely researched and used for decades, either as nutritional supplements or even actual medicines and are very popular with women suffering from CVI, water retention and cellulite. The dried aqueous extract of standardised red vine leaves (AS 195) is a food supplement available in capsules. Red vine leaf extract has been available in France for the treatment of symptoms associated with venous insufficiency. In the UK it is sold as a dietary supplement for the maintenance of healthy leg-vein circulation, in particular to avoid tired, heavy and aching legs that result from long periods of standing or sitting.