BEE VENOM CREAM - 30ml FAST RELIEF MUSCLE JOINT PAIN VERY EFFECTIVE

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Kim K, Jeong H, Lee G, Jang S, Yook T. Characteristics of Adverse Events in Bee Venom Therapy Reported in South Korea: A Survey Study. Toxins (Basel) 2021;14(1):18. View abstract. In susceptible individuals, using topical bee-venom products like serums and moisturizers can also cause adverse reactions, such as itching, hives, and redness ( 30, 31). Shen L, Lee JH, Joo JC, Park SJ, Song YS. Bee venom acupuncture for shoulder pain: a systematic review and meta-analysis of randomized controlled trials. J Pharmacopuncture 2020;23(2):44-53. View abstract. Lee EJ, Ahn YC, Kim YI, Oh MS, Park YC, Son CG. Incidence rate of hypersensitivity reactions to bee-venom acupuncture. Front Pharmacol 2020;11:545555. View abstract. Wesselius T, Heersema DJ, Mostert JP, et al. A randomized crossover study of bee sting therapy for multiple sclerosis. Neurology 2005;65:1764-8. View abstract.

de Jong NW, Vermeulen AM, de Groot H. Allergy to bumblebee venom. III. Immunotherapy follow-up study (safety and efficacy) in patients with occupational bumblebee-venom anaphylaxis. Allergy 1999;54:980-4. View abstract. Conrad VJ, Hazan LL, Latorre AJ, Jakubowska A, Kim CMH. Efficacy and safety of honey bee venom (Apis mellifera) dermal injections to treat osteoarthritis knee pain and physical disability: a randomized controlled trial. J Altern Complement Med 2019;25(8):845-55. View abstract.Hollister-Stier Laboratories LLC. Instructions and dosing schedule for allergenic extracts hymenoptera venom prodcts. No. 355120-HD1.

You agree to indemnify and hold Space NK (and its officers, directors, agents, subsidiaries, joint ventures, employees and third-party service providers, including but not limited to Bazaarvoice, Inc.), harmless from all claims, demands, and damages (actual and consequential) of every kind and nature, known and unknown including reasonable attorneys' fees, arising out of a breach of your representations and warranties set forth above, or your violation of any law or the rights of a third party. The anti-inflammatory effects of bee venom have been shown to especially benefit those with rheumatoid arthritis (RA), a painful inflammatory condition that affects your joints. Reduces the effects of eczema – Due to its anti-inflammatory properties, it has been found that bee venom can also reduce the itchiness and the severity of certain types of eczema 2.But before you panic, it’s harmless to you and no bees are hurt in this process. The venom is, instead, extracted using a soft glass pane that bees are encouraged to sting after they have been attracted to it by a gentle electric current.

Combining bee venom, stem cell technology and melittin peptide, this highly effective and lush eye cream acts to brighten dark areas underneath the eyes, smooth out fine lines and wrinkles, and repair the very delicate orbital area around the eyes. Park JH, Kim JG, Cha SH, Park SD. Eosinophilic foreign body granuloma after multiple self-administered bee stings. Br J Dermatol 1998,139(6):1102-5. View abstract. A 12-week study in 22 women demonstrated that applying a facial serum containing bee venom twice daily significantly reduced wrinkle depth and total wrinkle count, compared with the placebo ( 15). Rosman Y, Nashef F, Cohen-Engler A, Meir-Shafrir K, Lachover-Roth I, Confino-Cohen R. Exclusive bee venom allergy: risk factors and outcome of immunotherapy. Int Arch Allergy Immunol 2019;180(2):128-34. View abstract.BV has been explored in cancer ( 111, 112); melittin is considered cytolytic but non-specific. Melittin can break down the membrane lipid bilayer and exhibits toxicity when injected intravenously ( 113). APi M has the ability to suppress tumor growth in breast, liver, prostate, and lung cancer cells ( 111, 112). In vitro and in vivo studies show that melittin can suppress growth of cancerous cells by inhibiting NF-κB signaling and activating caspase 3 and 9 pathways. Inhibition of hepatocellular carcinoma cell motility was observed in vitro and in vivo by suppression of Rac1-dependent pathways ( 114). Anti-inflammatory Potential For any content that you submit, you grant Space NK a perpetual, irrevocable, royalty-free, transferable right and license to use, copy, modify, delete in its entirety, adapt, publish, translate, create derivative works from and/or sell and/or distribute such content and/or incorporate such content into any form, medium or technology throughout the world without compensation to you. Li JT, Yunginger JW. Management of insect sting hypersensitivity. Mayo Clin Proc 1992;67:188-94. View abstract. Manuka Honey – this is the honey produced by bees who pollinate the Manuka bush. Manuka Honey offers additional antiviral, anti-inflammatory and antioxidant benefits to your skin. The cream itself smells delicious, if you like honey, this has a rather intense honey scent which I love, its lightweight, smooths on well and after a minute or two has a mild cooling sensation which tells me it’s doing something good.Based on the results I’ve seen with Beelift I would recommend trying it for yourself.”

Park YC, Koh PS, Seo BK, et al. Long-term effectiveness of bee venom acupuncture and physiotherapy in the treatment of adhesive capsulitis: a one-year follow-up analysis of a previous randomized controlled trial. J Altern Complement Med 2014;20(12):919-24. View abstract. For me, micro-needling is a better place to start, and I wrote an article about it here, which you may find helpful if boosting collagen is your goal. Wound healing is a complex process and can be life threatening for those who are slow to heal such as those with diabetes. As such, research into the efficacy of different treatments is often undertaken. While research into wound healing has important applications it also has applications in the skincare world where these newly researched products may help to improve or support healing of open blemishes and other small wounds on the skin. Again it is important to remember that the concentration and type of bee venom used will often have a determining effect on the benefit and this research doesn’t yet indicate a new use.

An alternative to bee venom is neuropeptides which are becoming increasingly popular and provide the relaxing effects of botox without the sting as is experienced with a bee venom serum or cream. Melittin has been shown to suppress inflammatory pathways and reduce inflammatory markers, such as tumor necrosis factor alpha (TNF-α) and interleukin 1 beta (IL-1β) ( 10, 11). May reduce arthritis-related symptoms Low doses of BV trigger a range of anti-inflammatory responses that have been explored in diabetes, rheumatoid arthritis (RA), heart diseases, obesity, asthma, skin diseases, and central nervous system-associated diseases (Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis) ( 63, 64). BV suppresses inflammatory cytokines, including interleukin-6 (IL-6), IL-8, interferon-γ (IFN-γ), and tumor necrosis factor-α (TNF-α). A decrease in the signaling pathways responsible for the activation of inflammatory cytokines, nuclear factor-kappa B (NF-κB), extracellular signal-regulated kinases (ERK1/2) and protein kinase Akt, and Porphyromonas gingivalis lipopolysaccharide (PgLPS)-treated human keratinocytes are associated with melittin treatment( 65) ( Figure 2). Host Responses to Bee Venom