ADAPTIL Calm Home Diffuser with 30 Day Refill - Comfort, Calming and Anxious Dog, Anti-Stress, White, 48 ml (Pack of 1)

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ani12010122/s1, Supplementary methods; Table S1: Percentage of score reduction for each behavior, source of fear, or sign of stress; Table S2: Satisfaction with products and perceived effectiveness in all groups; Table S3: Summary of replies to specific questions in the study with collars; Table S4: Summary of replies to specific questions in the study with diffusers; Figure S1: Evolution of the global scores in puppies in the study with collars. Dog appeasing pheromone is a synthetic analog of a pheromone secreted by the intermammary sebaceous glands of the bitch after parturition and has a relaxing effect on puppies [ 4].

From the exploration of various calming diffusers to understanding how they work, it’s clear that these devices can make a significant difference in managing your dog’s anxiety. It is a drug-free and safe option that mimics a mother’s natural nursing pheromones to help dogs feel calm and comfortable. No preference was given for neutering, but most of the dogs in the collar study had not been neutered. When evaluating the latter, several parameters can skew the scoring, including how the owner is perceiving this behavior and how it impacts its quality of life. a, c) The global scores for the general behaviors and fears (sum of 17 scores—( a)) and the signs of stress (sum of 11 criteria—( c)) are plotted as median (plain line), first, and third quartiles (dotted lines below and above the median, respectively) for the groups of dogs receiving the reference diffuser (green) or Zenidog™ diffuser (blue).

Sergeant’s communications manager, Kelly Lytle Baehr, says the collars reproduce the calming pheromones nursing mothers release to soothe their babies. A: Neilson says pheromone products were first released for cats and were recommended to help marking or spraying and aggression problems, especially between cats in the same home. These underlying diseases could explain the lack of efficacy of the pheromone product perceived by some owners. Other questions related to the products’ characteristics and easiness of use, perceived effectiveness, overall impression, and satisfaction with the products were also asked during and at the end of the studies (See Supplementary Materials). Of note, all owners of dogs wearing an antiparasitic collar ( n = 37) reported no impact (or they did not know) of the pheromone collar on the antiparasitic collar apparent effectiveness or tolerance except for one owner, who saw parasites.

Taken individually, of the behaviors and sources of fear that were the most represented ( n≥ 8 in all groups), those that showed the highest improvement (based on the percentage of decrease of the median score by day 90, see Table S1) were as follows: “licks paws for no particular reasons” (−71%, −50%, and −43% in the groups with the reference collar and the ones with Zenidog™ collar without or with an antiparasitic collar, respectively); “jumps at the slightest noise” (−60%, −18%, and −43%, respectively); “is afraid of thunder or fireworks (−44%, −40%, and −50%, respectively); and “does not like to be alone” (−50%, −17%, and −25%, respectively). It can take between two weeks and a month to see an improvement in your pet’s stress levels, and it is also worth noting that some cats and dogs don’t seem to respond to the diffusers at all, and it is possible that your own pet will be among their number. The behavior that was the most observed was the dog licking its paws for no reason (no wound or parasites for example). It is, indeed, not always easy for owners to detect the stress signs in their dogs, some of them being very subtle and not necessarily recognized as a marker of stress [ 21].Four common sources of fear were also included, such as the fear of thunder and fireworks, the fear of car travel, the fear of other animals, and the fear of human separation.

Some diffusers also have settings that allow you to control the release of the pheromones, which can affect how long they last. Furthermore, the effectiveness of the Zenidog™ collar did not seem to be impacted by a concomitant antiparasitic collar worn by the dogs. A) Whilst other collars will not impair the effectiveness of the Adaptil collar, it is important to ensure that the Adaptil collar remains in close contact with the skin and is not covered by the other collar or bandana. Once you have contacted your vet and are reassured that there aren't any health conditions to be aware of, then diffusers and plug-ins are a great way to try to calm their nerves.

Available as a gel diffuser and a long-acting collar, ZENIDOG Pheromone Products contain an analogue of a dog-appeasing pheromone that is naturally emitted by nursing mother dogs.